What is Uterus?
Uterus (womb) is a hollow, inverted pear-shaped organ that accommodates the growing fetus during pregnancy. It is situated between the urinary bladder and rectum in the pelvic cavity and it is held in position by several uterine ligaments. It is made-up of mainly 3 tissue layers:
- the outermost, perimetrium (an extension of peritoneum that is composed of areolar connective tissue and forms few uterine ligaments and covers several organs in the pelvis);
- the middle layer, myometrium (composed of smooth muscle fibers that produce powerful coordinating contractions to expel the fetus during labor); and
- the innermost, endometrium (which is the site for endometrial cancer and is further divided into basal and functional layer). The functional layer is transient which develops and shed in cycles in response to mainly two hormones estrogen and progesterone until the menopause (cessation of menstrual cycles in women). The basal layer is permanent and gives rise to a new functional layer after each menstrual cycle.
What are the types of Endometrial Carcinoma?
Endometrioid adenocarcinomas are the most commonly encountered (about 95% of all cases) endometrial cancer. Other less common but aggressive subtypes of endometrial adenocarcinoma include clear-cell carcinoma, mucinous adenocarcinoma, and papillary serous adenocarcinoma. Most endometrial cancers develop from precancerous lesions known as endometrial hyperplasia (an abnormally increased growth of endometrium). Endometrial hyperplasia is divided into four subtypes: simple hyperplasia, complex hyperplasia, simple atypical hyperplasia, and complex atypical hyperplasia. The risk of developing endometrial cancer is highest (about 29%) in complex atypical hyperplasia. All the pre-cancerous lesions are generally treated to avoid a development into invasive disease.
Best Endometrial (Uterine) Cancer Specialist in Delhi
Dr Sunny Garg is a renowned Medical Oncologist in New Delhi with an experience of around 10 years of treating uterine cancer patients. He has treated endometrial cancer patients with Chemotherapy, Targeted Therapy, Hormonal Therapy, and Personalized Cancer Treatment. He is currently practicing at Manipal Hospital, Dwarka.
Diagnostic modalities available at our hospital include Hysteroscopy, Endometrial Biopsy, CT Guided Biopsy, Transvaginal Ultrasound, Whole Body PET CT, etc. Other treatment facilities for Endometrial Cancer available are Radical Hysterectomy, Radiation Therapy, etc.
Call +91 9686813020 for appointment.